
Adenosine and Sleep Pressure: The Molecular Science of Why You Get Tired
Explains how adenosine — a metabolic byproduct of neuronal energy use — accumulates during wakefulness, binds to distinct receptor subtypes to suppress arousal and gate sleep, and why only slow-wave sleep fully resolves this pressure; covers the dissociable roles of A1 and A2A receptors, the mechanics of the caffeine mask, and what chronic caffeine use does to the adenosine system.






